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Colchicine 500 Microgram tablets 28 Tablets

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Are you looking to buy Colchicine online? Colchicine is an anti-gout agent, it is used to treat gout attacks and prevent attacks when treatment is started with other medications. The price shown is for 100 tablets. Colchicine can be bought online from Pharmacy Direct GB and is UK sourced.

28 Tablets (1 pack)
56 Tablets (2 packs)
84 Tablets (3 packs)
112 Tablets (4 packs)

This information is for learning purposes only until you have completed a medical questionnaire about your condition. You will be able to select this as a preferred treatment to buy only when you've submitted the questionnaire for our prescribers to check. Product supplied may be from a different manufacturer.

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How Does Colchicine 500mg Tablets Work?

Colchicine is a medication primarily used to treat gout and certain other conditions associated with inflammation. It is derived from the Colchicum autumnale plant, also known as the autumn crocus or meadow saffron. Colchicine has been used for centuries to relieve the pain and inflammation associated with gout, a form of arthritis caused by the accumulation of uric acid crystals in the joints.

The primary actions of Colchicine include reducing inflammation and preventing the formation of uric acid crystals in the joints. It works by inhibiting the movement of white blood cells to the inflamed area, which can help alleviate gout symptoms.

In addition to gout, Colchicine may also be prescribed to manage other medical conditions, such as familial Mediterranean fever and pericarditis (inflammation of the lining around the heart). It is typically available in tablet or capsule form and should be taken as directed by a healthcare provider.

What Does Colchicine 500mg Tablet Treat?

  • Sudden, intense joint pain
  • Swelling
  • Redness
  • Gout


  • Do not take the tablets if you are pregnant or breastfeeding without the approval of your doctor.
  • Do not take the tablet if you are allergic to the ingredients it contains.
  • Do not take if you are taking any other medications, including over the counter medications and supplements without informing your doctor.
  • If you have been diagnosed with a blood clotting disorder or liver disease, you must not use the tablet without the approval of your doctor.


  • Colchicine comes as a tablet to be taken by mouth.
  • It is usually taken once a day, four times a day with or without food.
  • Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
  • Swallow one tablet whole with water once daily.
  • The dose can be taken at any time of day, but it is best to take it at the same time each day to maintain consistency.
  • If you miss a dose, you can take it as soon as you remember, unless it is close to the time for your next dose, in which case you should just skip the missed dose and continue with your regular schedule.


  • Active Ingredients: The active ingredient is Colchicine.
  • Inactive Ingredients: The inactive ingredients are stearic acid, talc, maize starch, and lactose.

Side Effects

  • Insomnia
  • Drowsiness
  • Nausea
  • Diarrhoea
  • Abdominal pain

Colchicine Frequently Asked Questions

  • What is Colchicine used for? Colchicine is primarily used to treat gout, a type of arthritis caused by the buildup of uric acid crystals in the joints. It can also be used to manage familial Mediterranean fever and pericarditis. 
  • How does Colchicine work? Colchicine works by reducing inflammation and preventing the formation of uric acid crystals in the joints. It does this by inhibiting the movement of certain white blood cells to the affected area.
  • What is the typical dosage of Colchicine? The typical dosage for acute gout is usually 1.2 mg to 2.4 mg initially, followed by a lower maintenance dose. The dosage for other conditions may vary, so it's essential to follow your doctor's instructions.
  • Are there any side effects associated with Colchicine? Common side effects of Colchicine can include nausea, vomiting, diarrhea, and abdominal pain. Serious side effects can occur, so it's important to report any unusual symptoms to your healthcare provider.
  • Can I take Colchicine for prevention or as needed? Colchicine is typically prescribed for acute gout attacks or for specific conditions, and it's not recommended for routine use or as a preventive measure. Always follow your doctor's guidance on its use.
  • Can I take Colchicine with other medications? Colchicine can interact with other medications, so it's crucial to inform your healthcare provider about all the medications and supplements you are taking to avoid potential drug interactions.
  • How should I take Colchicine tablets? Take Colchicine as directed by your healthcare provider. It can be taken with or without food. Do not crush, chew, or break the tablets unless your doctor advises otherwise.
  • Can I drink alcohol while taking Colchicine? It's generally advisable to limit alcohol consumption, especially during a gout attack. Alcohol can exacerbate gout symptoms. Discuss your alcohol use with your healthcare provider.
  • Can I stop taking Colchicine once my symptoms improve? It's essential to complete the course of Colchicine as prescribed by your doctor, even if your symptoms improve. Stopping the medication prematurely can lead to a recurrence of symptoms.
  • What should I do if I miss a dose of Colchicine? If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed one. Do not double the dose to make up for a missed one.

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