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Tadalafil is a generic, unbranded version of Cialis, a very popular erectile dysfunction treatment. Tadalafil is the active ingredient in Cialis, meaning that they are medically equivalent; however, Tadalafil is accessible at a much lower cost. At Pharmacy Direct, our Tadalafil 5mg price is UK-leading. You can buy Tadalafil UK online.
When a man is sexually stimulated, nitric oxide is released in the body to enable the production of cyclic guanosine monophosphate (cGMP), which controls the dilation and contraction of the blood vessels that carry blood to and from the penis. When the blood vessels that allow blood to flow into the penis enlarge and those that remove blood contract, the penis fills with blood and an erection occurs and is maintained. An enzyme called phosphodiesterase-5 (PDE5) destroys cGMP, which causes the blood vessels to return to their normal size and ends the erection. Tadalafil prevents PDE5 from destroying cGMP, which causes the erection to last for longer. Tadalafil is active in the body for up to 36 hours, leading it to become known as “the weekend pill”. In addition to treatment for erectile dysfunction, Tadalafil may be used to treat benign prostate hyperplasia (BPH) and pulmonary arterial hypertension.
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